IGAMI Technology - Application Fields:

Ion Channel Cell Lines • Production Cell Line Development

 

Ion Channel Cell Lines

  The expression of recombinant proteins can lead to selective negative growing pressure. Cells expressing recombinant ion channel membrane proteins are especially prone to loosing their expression ability after few passages even under selection pressure.

The IGAMI technology enables the fast generation of ion channel CHO-K1 cell lines with long term expression stability.

The IGAMI technology was successfully used in development of several ion channel cell lines like

  • Potassium Channels
  • Calcium Channels
  • Transient Receptor Potential Channels
  • Ligand Gated Channels

Kv1.5

 


 


TRPC

 

 

 

 

Production Cell Line Development